The IMAC is in possession of several new, state-of-the-art mass spectrometers that are coupled to liquid chromatography (LC) or gas chromatography (GC) separation systems.
 |
TSQ Altis Liquid Chromatography – Mass Spectrometer (Thermo Scientific) offers improvements in the ion source, mass analyzer and RF electronics to offer high sensitivity, reduced noise, and more data points with high SRM rates compared to previous generation instruments. Segmented quadrupoles enhance ion transmission and consistency to ensure superb sensitivity. This triple quadrupole mass spectrometer is used for Targeted Metabolomics (Quantification). We use Trace Finder Software for data analysis which allows for an array of capabilities in performing targeted screening and quantification. |
Q-Exactive Plus Orbitrap Liquid Chromatography – Mass Spectrometer (Thermo Scientific). This system is a High Resolution Accurate Mass instrument and has the ability to routinely and confidently identify, quantify, and confirm in a single analysis using a single mass spectrometer. This high resolution mass spectrometer is used for Untargeted Metabolomics (Discovery). We use Compound Discoverer software series for data acquisition, analysis and small molecule identification.
TSQ Quantiva Liquid Chromatography – Mass Spectrometer (Thermo Scientific) uses active ion management to exceed even the most stringent analytical requirements with high sensitivity, speed, and dynamic range. Selected reaction monitoring (SRM) uses collision-induced dissociation which is used as a means to increase selectivity. This triple quadrupole mass spectrometer is used for Targeted Metabolomics (Quantification). We use Trace Finder Software for data analysis which allows for an array of capabilities in performing targeted screening and quantification.
TSQ 8000 EVO Gas Chromatography – Mass Spectrometer (Thermo Scientific) is another triple quadrupole instrument and is used for both Targeted and Untargeted Metabolomics.